Preview Roundups
May 21, 2025
Cincinnati at Pittsburgh 12:35 PM ET
A day after snapping a four-game losing streak, the Pittsburgh Pirates will try to string together back-to-back wins for the first time in nearly a month when they host the Cincinnati Reds in the rubber match of a three-game series on Wednesday afternoon.
Houston at Tampa Bay 1:10 PM ET
Houston Astros right-hander Hunter Brown did everything but win in his most recent outing.
Chi. Cubs at Miami 1:10 PM ET
After turning in one of their most complete efforts of the season, the Chicago Cubs face the host Miami Marlins in the rubber match of a three-game series on Wednesday afternoon.
Baltimore at Milwaukee 1:10 PM ET
The task of halting the Orioles' eight-game slide falls on veteran right-hander Tomoyuki Sugano as Baltimore looks to avoid being swept by the host Milwaukee Brewers on Wednesday in the finale of the three-game series.
Detroit at St. Louis 1:15 PM ET
The Detroit Tigers planned on giving pitcher Jack Flaherty another chance to face his former team this week in St. Louis.
Seattle at Chi. White Sox 2:10 PM ET
The Seattle Mariners will look to bounce back from their second shutout loss of the season when they bid to secure a road series victory from the Chicago White Sox on Wednesday afternoon.
Kansas City at San Francisco 3:45 PM ET
Logan Webb will hope to prolong the Kansas City Royals' offensive slump and earn the San Francisco Giants their sixth win to close a nine-game homestand when he takes the mound on Wednesday afternoon.
Cleveland at Minnesota 4:10 PM ET
After two days of watching the sky dump buckets of rain across Minneapolis, the Cleveland Guardians and Minnesota Twins are eager to play ball.
NY Mets at Boston 6:45 PM ET
The visiting New York Mets will have to generate more offense if they're going to beat the Boston Red Sox on Wednesday night and avoid a three-game sweep.
Texas at NY Yankees 7:05 PM ET
Jacob deGrom's velocity is slightly diminished but he appears as effective as ever after returning from a second Tommy John surgery.
San Diego at Toronto 7:07 PM ET
The Toronto Blue Jays likely will need more than three hits on Wednesday against the visiting San Diego Padres if they want to clinch a series victory.
LA Angels at Athletics 10:05 PM ET
The streaking Los Angeles Angels are experiencing fun times in their first visit to West Sacramento, Calif.
Arizona at LA Dodgers 10:10 PM ET
With a four-game losing streak now behind them, the Los Angeles Dodgers will be out to win a series against the visiting Arizona Diamondbacks when the teams meet in the finale of a three-game set Wednesday.