Jean Segura hit a walk-off single to right field in the 11th inning, lifting the host Philadelphia Phillies past the Arizona Diamondbacks 7-6 on Friday.

Bryce Harper hit a two-run homer and doubled, and Brad Miller added a two-run, game-tying home run for Philadelphia in the 10th inning.

Ketel Marte socked a two-run homer for Arizona in the top of the 10th after teammate Christian Walker tied the game in the ninth with a two-run blast.

J.T. Realmuto added two hits and two RBIs for the Phillies, who snapped a three-game losing streak. Segura also had two hits.

The Phillies had dropped their previous four meetings with the National League-worst Diamondbacks this season.

Phillies starter Aaron Nola tossed 5 1/3 solid innings, allowing three hits and two runs with seven strikeouts and no walks.

Enyel De Los Santos (1-1) earned the win despite allowing Marte's homer.

Walker, who had four hits Thursday, tied the game off Phillies closer Ian Kennedy in the ninth.

Diamondbacks starter Taylor Widener gave up five hits and two runs with four strikeouts and three walks in five innings.

Taylor Clarke (1-1) took the loss.

The game was delayed 26 minutes from the start for contact tracing after the Phillies placed Zach Eflin, Andrew Knapp and Luke Williams on the COVID-related injured list.

The Phillies jumped out to a 2-0 lead in the third inning when Harper blasted a two-run homer to left-center field. It was his 25th long ball of the season.

The Diamondbacks managed just one hit through the first five innings, a second-inning single by David Peralta.

Arizona's Nick Ahmed opened the sixth with a single to left. One out later, Josh Rojas ripped an RBI triple to right to cut the deficit to 2-1. After Nola was replaced by Connor Brogdon, Josh VanMeter lofted a sacrifice fly to center to tie the game at 2.

The Phillies loaded the bases with one out in the seventh and Realmuto responded with a two-run single for a 4-2 lead.

The Diamondbacks had runners on first and third with no outs in the eighth before Hector Neris retired the next three batters without yielding a run.

--Field Level Media