Dwight Smith Jr. hit a grand slam, Trey Mancini added a two-run shot and the Baltimore Orioles defeated the visiting San Francisco Giants 9-6 on Friday night.

Renato Nunez provided some insurance for Baltimore with a solo homer in the seventh inning to close out the scoring.

Former Orioles farmhand Mike Yastrzemski hit his first major league homer and tripled for the Giants.

Andrew Cashner (6-2) survived a five-run first inning and gave up six runs on eight hits in five innings.

Three Orioles relievers strung together four innings of one-hit relief, with Richard Bleier picking up his second save.

Giants starter Drew Pomeranz (1-6) only got four outs and allowed eight runs on six hits. Over his past five starts, Pomeranz is 0-4 and has allowed 25 runs on 28 hits and 11 walks in just 13 2/3 innings.

The teams combined for 11 runs in the first inning, with the Giants scoring five.

After Joe Panik walked, Yastrzemski tripled him home and scored on a single by Buster Posey. The Giants loaded the bases on Pablo Sandoval's single and Evan Longoria's walk.

Brandon Crawford's sacrifice fly scored Posey and Kevin Pillar's infield single reloaded the bases before Steven Duggar capped in the inning with a two-run single to left.

The Orioles went the Giants one better in the first inning, scoring six runs on four hits and two San Francisco errors.

After RBI singles by Nunez and Pedro Severino made it 5-2, Keon Broxton drew a two-out walk to load the bases and Smith followed by launching a 2-1 fastball to center for his 10th homer of the season.

It was the first time since the franchise moved to Baltimore in 1954 that the Orioles and their opponent each scored at least five runs in the first inning of a game.

Yastrzemski tied it when he homered off the first pitch of the second inning, but Mancini's two-run shot in the bottom of the second made it 8-6.

--Field Level Media